Mike Allen interviews Axios CEO Jim VandeHei about his year as an “AI lab rat,” from feeding AI personal, medical, and business data to testing what it can actually do. Jim explains why he thinks AI is more powerful than most people realize, why it is still messy inside companies, and what the experiment revealed about work, health, anxiety, and the next class of AI-powered employees. Timestamps: 00:00 - AI should challenge your thinking 00:37 - Why Jim became an AI lab rat 01:19 - What AI knows about Jim 03:53 - How Jim uses AI agents 05:49 - How to build your own personal AI 09:14 - Don’t outsource your thinking 11:05 - What AI agents can actually do 13:24 - Why AI still feels clunky 15:02 - Why the AI job panic may be wrong 17:19 - The rise of AI super-workers 19:17 - How anyone can start using AI 23:27 - How AI changed Jim’s writing 27:22 - Why Jim trusts AI with health questions 29:02 - Be curious and humble about AI 31:46 - How AI changed Jim’s mind and mood 33:17 - What AI makes possible now