The US and Israel launched airstrikes against Iran Saturday morning and again on Sunday morning local time, killing Iranian Supreme Leader Ayatollah Ali Khamenei, President Trump confirmed. Four members of the Iranian supreme leader’s family were also killed. The airstrikes are a response to the regime’s refusal to dismantle its nuclear program following weeks of talks — and as the US increased its military presence in the Middle East after President Trump warned Tehran there would be consequences if a deal was not reached. Israel later confirmed that the joint strikes targeted the Supreme Leader and Iran’s President Masoud Pezeshkian.