Saturday Night Live alum Victoria Jackson, who veteran fans may remember from impersonating stars like Madonna and Roseanne Barr during her 1986-1992 tenure on the long-running NBC show, has announced that her stage 4 cancer is inoperable. She is hoping to extend her time with a CDK4/6 inhibitor, a promising drug in the form of a tablet that targets proteins in cancer cells to keep them from growing.