To help you determine if you are suffering from burnout, Richard Holmes, Director of Wellbeing at Westfield Health, has given us a round-up of the most common signs. Fatigue. One of the most common signs of burnout is persistent tiredness, which is likely impacting your everyday life. "With high levels of stress come stress hormones: cortisol and adrenaline. Constant elevation of these hormones can make you feel incredibly deflated.”