In 2022, 175 countries resolved to develop a global plastics treaty and to fast-track negotiations to deliver the agreement by end 2024. This is a historic opportunity to unlock the systemic change needed to tackle the plastic crisis and end plastic pollution once and for all. As we enter the final lap of the negotiations, what are the essential elements and issues that ensure a comprehensive, robust and inclusive agreement to effectively protect human health and the environment? <i>Simultaneous interpretation in English and Spanish<i>